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PBSuite

This currently hosts two projects created and maintained by Adam English.

PBJelly – the genome upgrading tool.
PBHoney – the structural variation discovery tool

Both are contained within the PBSuite code found in downloads.

—– PBJelly —–
Read The Paper
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0047768

PBJelly is a highly automated pipeline that aligns long sequencing reads (such as PacBio RS reads or long 454 reads in fasta format) to high-confidence draft assembles. PBJelly fills or reduces as many captured gaps as possible to produce upgraded draft genomes.

—– PBHoney —–
Read The Paper
http://www.biomedcentral.com/1471-2105/15/180/abstract

PBHoney is an implementation of two variant-identification approaches designed to exploit the high mappability of long reads (i.e., greater than 10,000 bp). PBHoney considers both intra-read discordance and soft-clipped tails of long reads to identify structural variants.

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Website https://hgsc-vmweb-08.hgsc.bcm.edu/software/honey
Tags
License
Features
  • Genome Assembly
  • Genome Upgrade
  • Structural Variation
  • Assembly Evaluation