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COMER is a protein sequence alignment tool designed for protein remote homology detection. It accepts a multiple sequence alignment as input and converts it into the profile to search a profile database for statistically significant similarities. COMER is licensed under the GNU GP License, version 3. Please find its archive file, download and extract it with the command “tar -zxf “, and refer to the README file for instructions on how to use the software.

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Website https://comer.sourceforge.io