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GeneNetWeaver

Posted on 0 Comments Bio-Informatics
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GeneNetWeaver (GNW) is an open-source tool for in silico benchmark generation and performance profiling of network inference methods. GNW was used to generate the community-wide DREAM3, DREAM4 and DREAM5 In Silico Challenges.

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Post Views: 273
Website http://gnw.sourceforge.net
Tags
License MIT License
Platform Linux Mac Windows
Features
  • Extraction of modules from known transcriptional regulatory networks (E.coli, Yeast, etc.)
  • Generation of realistic in-silico gene network benchmarks for network inference methods
  • Simulation of realistic biological experiments (knowckout, knockdown, dual-knockout, multifactorial perturbations, time series, etc.)
  • Performance evaluation of network predictions (Precision-Recall, ROC, motif analysis)

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