qure

QuRe is a program for viral quasispecies reconstruction, specifically developed to analyze long read (>100 bp) NGS data. The software performs alignments of sequence fragments against a reference genome, finds an optimal division of the genome into sliding windows based on coverage and diversity and attempts to reconstruct all the individual sequences of the viral quasispecies–along with their prevalence–using a heuristic algorithm, which matches multinomial distributions of distinct viral variants overlapping across the genome division. QuRe comes with a built-in Poisson error correction method and a post-reconstruction probabilistic clustering, both parameterized on given error rates in homopolymeric and non-homopolymeric regions.

Today’s small-to-medium-sized (SMB) businesses and large enterprises are saving on their monthly communications costs by making one simple decision: to switch to a VoIP service solution from their old, outdated Plain Old Telephone Service (POTS). By choosing a new VoIP service, these companies enjoy the flexibility, reliability, call features, and audio quality that only a VoIP service can provide. Plus, they cut their phone bill by up to 70%!