Toxtree: Toxic Hazard Estimation

A GUI application which estimates toxic hazard of chemical compounds. The latest version includes the following toxicity prediction modules:

-Cramer rules (oral toxicity)
-Toxicity mode of action via Verhaar scheme
-Skin irritation and Eye irritation prediction
-Benigni / Bossa rulebase for mutagenicity and carcinogenicity prediction
-START biodegradation and persistence prediction
-Skin sensitisation reactivity domain
-Kroes TTC Decision tree
-SMARTCyp – Cytochrome P450-Mediated Drug Metabolism and metabolites prediction
-Structure Alerts for the in vivo micronucleus assay in rodents (ISSMIC)
-Structural Alerts for Functional Group Identification (ISSFUNC)
-Structural alerts associated with covalent protein binding and DNA binding.
– Ames mutagenicity

Toxtree provides a plugin framework to incorporate different approaches to the estimation. Platform independent (written in Java), with the use of The Chemistry Development Kit.

Cloudbased voice solutions are common in enterprise networks and frustrating for operations teams to manage. Simplify VoIP monitoring by having a proactive analysis of on-prem, hybrid and UCaaS voice services. Try the ThousandEyes VoIP monitoring solution today, free.